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Research and development of ophthalmic surgical techniques |
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Chapter 8: Perioperative topical and systemic therapy
A standard therapy regiment for penetrating keratoplasty patients is gentamycin ointment at the evening before surgery, and after surgery chloramphenicol 0.5% three times daily for one month, and dexamethasone 0.1% six times daily for one month, tapering to one time daily at one year. In our series of deep anterior lamellar keratoplasty patients, the same perioperative therapy regiment was followed. Steroid therapy may be tapered sooner, because the risk of endothelial allograft rejection is eliminated.
In patients with recurrent herpetic keratitis acyclovir 400 mg three times daily was given for six months or more. When indicated, immunosuppressive therapy was prescribed.
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