A standard therapy regiment for penetrating keratoplasty patients is gentamycin ointment at the evening before surgery, and after surgery chloramphenicol 0.5% three times daily for one month, and dexamethasone 0.1% six times daily for one month, tapering to one time daily at one year. In our series of posterior lamellar keratoplasty patients, the same perioperative therapy regiment was followed. Steroid therapy may be tapered sooner, because the risk of endothelial allograft rejection may be reduced by the absence of corneal sutures.